Computer Modeling of Biomolecules
Presented by
Kam Bo Wong
Department of Biochemistry & Molecular Biotechnology Programme
email: kbwong@cuhk.edu.hk
http://smart.bch.cuhk.edu.hk/kbwong/index.htm
10. Getting PDB files from the internet.
10.1 Protein structure files can be downloaded from the Protein Data Bank.
Try searching for hemoglobin:
10.2 Search Results
All entries in the PDB is identified by a four-letter code.
For example, the PDB code for the insulin is '3ins'. Try click the
"EXPLORE" button of the 1A00 entry.
10.3 Click "Download/Display File".
10.4 Save the PDB file
· Save the file as 1A00.pdb
· Try to practise what you have learnt to view the file 1A00.pdb and try to answer the following questions:
1. Hemoglobin is composed of how many polypeptide
chains?
2. Does hemoglobin contain any beta-sheet?