Revision Questions : Work of a vaccine

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Question 1: Which of the following criteria must be fulfilled for a vaccine to be effective?
    1. It contains an antigen that triggers the primary immune response but not causing disease.
    2. It must be lifetime lasting.
    3. It can induce both the humoral immune response and cell mediated immune response.
    4. It must be able to be administered intramuscularly.
  • CORRECT! To trigger the formation of memory cells in the body is the most important criteria for a vaccine.
  • INCORRECT! Whether it is lifetime lasting depends on how long the memory cells can persist.
  • INCORRECT! Whether it is lifetime lasting depends on how long the memory cells can persist; it is not necessary to trigger both immune response everytime.
  • INCORRECT! Whether it is lifetime lasting depends on how long the memory cells can persist; it is not necessary to trigger both immune response everytime; vaccine can be administered orally or through other routes.
Question 2: The reason of using isolated protein from virus (subunit vaccine) over the whole virus is/are because
    1. It contains antigens of the virus.
    2. It triggers a stronger immune response.
    3. It cannot reproduce in the host.
    4. It would not trigger allergic response.
  • INCORRECT! They trigger the same strength of immune response.
  • CORRECT! It contains the antigen for immune response but cannot reproduce in the host, so it is safer to use isolated protein.
  • INCORRECT! They trigger the same strength of immune response and both can trigger allergic response.
  • INCORRECT! They both can trigger allergic response.
Question 3: DNA vaccine contains _____ DNA for coding _____ antigens inside the cell which triggers immune response.
  • INCORRECT! It should be microbial DNA.
  • INCORRECT! It should be microbial DNA and it codes for protein.
  • CORRECT! Bacterial DNA cloned to a vector is injected into the body for expressing the protein antigen.
  • INCORRECT! DNA doesn't code for polysaccharides.
Question 4: Stephen is a 6-month old boy who receives breastfeeding from his mother, he is immune to chicken-pox since he receives antibody from his mother's milk. This kind of immunity is
  • INCORRECT!
  • INCORRECT!
  • INCORRECT!
  • CORRECT!
Question 5: You should not take a vaccine if you are
  • INCORRECT! You can still take a vaccine.
  • INCORRECT! You can still take a vaccine.
  • INCORRECT! There is no association between vaccine and milk allergy. However, if one has egg allergy, he/she should consult a doctor before taking the vaccine.
  • CORRECT! This may be life threatening if allergic to a vaccine.