Selected Publications (as corresponding author)

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1. Choi AK, Wong EC, Lee KM, Wong KB. (2015) Structures of Eukaryotic Ribosomal Stalk Proteins and Its Complex with Trichosanthin, and Their Implications in Recruiting Ribosome-Inactivating Proteins to the Ribosomes. Toxins, 7, 638-647.
   
2. Luo F, Fong YH, Zeng Y, Shen J, Jiang L, Wong KB. (2014) How vacuolar sorting receptor proteins interact with their cargo proteins: crystal structures of apo and cargo-bound forms of the protease-associated domain from an Arabidopsis vacuolar sorting receptor. Plant Cell, 26, 3693-708
   
3. Fong YH, Wong HC, Yeun MH, Lau PH, Chen YW, Wong KB. (2013) Structure of UreG/UreF/UreH complex reveals how urease accessory proteins facilitate maturation of Helicobacter pylori urease. PLoS Biol, 11, e1001678.
   
   
4. Lee KM, Yusa K, Chu LO, Yu, CWH, Oono M, Miyoshi T, Ito K, Shaw PC, Wong KB, Uchiumi T. (2013) Solution structure of human P1-P2 heterodimer provides insights into the role of eukaryotic stalk in recruiting ribosome-inactivating protein trichosanthin to the ribosome. Nucleic Acids Res, 41, 8776-8787
   
5. Chuck CP, Chen C, Ke Z, Wan DC, Chow HF, Wong KB. (2013) Design, synthesis and crystallographic analysis of nitrile-based broad-spectrum peptidomimetic inhibitors for coronavirus 3C-like proteases. Eur J Med Chem, 59:1-6.
   
6. Chan, KH, Lee, KM, Wong KB. (2012) Interaction between hydrogenase maturation factors HypA and HypB is required for [NiFe]-hydrogenase maturation. PLoS One, 7:e32592.
   
7. Lee, K.M., Yu, W.H., Chiu, Y.H., Sze, K.H., Shaw, P.C., Wong, K.B. (2012) Solution structure of the dimerization domain of the eukaryotic stalk P1/P2 complex reveals the structural organization of eukaryotic stalk complex, Nucleic Acids Res, 40:3172-82.
   
8. Chan, K.H., Li, T., Wong, C.O., Wong, K.B. (2012) Structural Basis for GTP-Dependent Dimerization of Hydrogenase Maturation Factor HypB, PLoS One 7, e30547.
9. Chan, C.H., Wilbanks, C.C., Makhatadze, G.I., Wong, K.B. (2012) Electrostatic Contribution of Surface Charge Residues to the Stability of a Thermophilic Protein: Benchmarking Experimental and Predicted pKa Values, PLoS One 7, e30296.
   
10. Fong, Y.H., Wong, H.C., Chuck, C.P., Chen, Y.W., Sun, H., Wong, K.B. (2011) Assembly of the preactivation complex for urease maturation in Helicobacter pylori: Crystal Structure of the UreF/UreH complex, J. Biol. Chem. 286, 43241 (Selected as paper of the week).
11. Chuck, C.P., Chow, H.F., Wan, C.C., Wong, K.B. (2011) Profiling of Substrate Specificities of 3C-Like Proteases from Group 1, 2a, 2b, and 3 Coronaviruses, PLoS One, 6, e27228
    Chan C.H., Yu, T.H., Wong, K.B. (2011) Stabilizing salt-bridge enhances protein thermostability by reducing the heat capacity change of unfolding. PLoS One 6, e21624.
12. Chan K.H., Wong, K.B. (2011) Structure of an essential GTPase, YsxC, from Thermotoga maritima, Acta Cryt. F 67, 640.
13. Lam SY, Yeung RCY, Yu TH, Sze KH, Wong KB: A Rigidifying Salt-Bridge Favors the Activity of Thermophilic Enzyme at High Temperatures at the Expense of Low-Temperature Activity. PLoS Biol 2011, 9:e1001027
    
14. Lee KM, Yu CW, Chan DS, Chiu TY, Zhu G, Sze KH, Shaw PC, Wong KB. (2010) Solution structure of the dimerization domain of ribosomal protein P2 provides insights for the structural organization of eukaryotic stalk. Nucleic Acids Res, 38:5206-5216.
15. Chuck CP, Chong LT, Chen C, Chow HF, Wan DC, Wong KB (2010) Profiling of substrate specificity of SARS-CoV 3CL. PLoS One, 5:e13197.
16. Too PH, Ma MK, Mak AN, Wong YT, Tung CK, Zhu G, Au SW, Wong KB, Shaw PC. (2009) The C-terminal fragment of the ribosomal P protein complexed to trichosanthin reveals the interaction between the ribosome-inactivating protein and the ribosome. Nucleic Acids Res, 37:602-610.
17. Tang WK, Wong KB, Lam YM, Cha SS, Cheng CH, Fong WP. (2008) The crystal structure of seabream antiquitin reveals the structural basis of its substrate specificity. FEBS Lett, 582:3090-3096.
18. Chan DS, Chu LO, Lee KM, Too PH, Ma KW, Sze KH, Zhu G, Shaw PC, Wong KB (2007) Interaction between trichosanthin, a ribosome-inactivating protein, and the ribosomal stalk protein P2 by chemical shift perturbation and mutagenesis analyses. Nucleic Acids Res, 35:1660-1672.
19. Yeung RC, Lam SY, Wong KB (2006) Crystallization and preliminary crystallographic analysis of human common-type acylphosphatase. Acta Cryst, F62:80-82.
20. Lee KM, Ma KW, Shaw PC, Wong KB (2006) A high-yield one-step purification method using copper-chelating chromatography for recombinant proteins fused with maltose-binding protein. Anal Biochem, 358:152-154.
21. Lee CF, Makhatadze GI, Wong KB (2005) Effects of charge-to-alanine substitutions on the stability of ribosomal protein L30e from Thermococcus celer. Biochemistry, 44:16817-16825.
22. Lee CF, Allen MD, Bycroft M, Wong KB (2005) Electrostatic interactions contribute to reduced heat capacity change of unfolding in a thermophilic ribosomal protein L30e. J Mol Biol, 348:419-431.
23. Cheung YY, Lam SY, Chu WK, Allen MD, Bycroft M, Wong KB (2005) Crystal structure of a hyperthermophilic archaeal acylphosphatase from Pyrococcus horikoshii--structural insights into enzymatic catalysis, thermostability, and dimerization. Biochemistry, 44:4601-4611.
24. Ip DT, Chan SH, Allen MD, Bycroft M, Wan DC, Wong KB (2004) Crystallization and preliminary crystallographic analysis of a novel orange fluorescent protein from the Cnidaria tube anemone Cerianthus sp. Acta Cryst, D60:340-341
25. Wong KB, Lee CF, Chan SH, Leung TY, Chen YW, Bycroft M (2003) Solution structure and thermal stability of ribosomal protein L30e from hyperthermophilic archaeon Thermococcus celer. Protein Sci, 12:1483-1495.
26. Chen YW, Bycroft M, Wong KB (2003) Crystal structure of ribosomal protein L30e from the extreme thermophile Thermococcus celer: thermal stability and RNA binding. Biochemistry, 42:2857-2865.