Home | Kong Siu Kai Research Group
The Chinese University of Hong Kong | Biochemistry Programme| School of Life Science

 

Research Grants

  • 2016, NSFC/RGC Joint Research Scheme (PI), Investigation of technology and mechanism of in/ex vivo stem-cell differentiation by femtosecond laser. HKD 1,020,000.
  • 2015, HMRF (Co-I), Rapid Sample-to-answer Smart Lab-on-a-disc Pharmacogenetic Testing Device for Personalised Medicine. HKD 988,328.
  • 2014, Vice-Chancellor's One-off Discretionary Fund (Co-I), Functional Plasmonics with Energy Localization for Sensing, Nano-Actuation and Optoelectronics. HKD 2,800,000.
  • 2014, UGC Scheme C Funding (Co-I), Establishment of New Paradigm with Feasible Models in Teaching and Learning Science for Problem Solving and Future Development. HKD 2,637,000.
  • 2014, HMRF (Co-I), Development and Pilot Study of monoclonal Antibodies for Rapid Screening of HLA-B*15:02 to Enable Safer Use of Carbamazepine. HKD 675,158.
  • 2014, GRF (Co-I), A Novel Combination Therapy for Treating Osteoporosis - A Mechanistic Study on the Synergistic Bone Anabolic Effects of HMG CoA Reductase Inhibitor and Vitamin D. HKD 770,769
  • 2014, GRF (Co-I), Lab-in-droplet Bioassay Strategy with Power-enabled Lab-on-a-disc. HKD 500,000
  • 2014, ITF (PI), Development of a Label-free Non-PCR Technology for Rapid Infectious Disease Diagnosis. HKD 987,050.
  • 2013, GRF (PI), To Develop A Microfluidic Device for Testing Allergy. HKD 724,500.
  • 2013, CRF (Co-I), Funtional Plasmonics with Energy Localization for Sensing, Nano-actuation and Optoelectronics. HKD 5,000,000
  • 2013, AoE (Co-I). Novel Wave Functional Materials for Manipulating Light and Sound. HKD 2,779,000.
  • 2011, GRF (PI), To develop an aptamer-based surface plasmon resonance biosensor to detect apoptosis for anticancer drug discovery, HKD 855,437.
  • 2010, HHSRF (Co-I), A mechanistic study of Scutellaria baicalensis Georgi(Huangqin) and rosiglitazone coadministration on the treatment of type 2 diabetes mellitus. HKD 988,728.
  • 2010, GRF (Co-I), High precision and high efficiency laser induced cell-cell fusion assisted by nanorods. HKD 642,400.
  • 2010, GRF (PI), The oncogenic pathway of riboregulator H19: From microRNA to DNA methylation. HKD 1,100,000.
  • 2010, Funding from the CUHK Research Committee Group Research Scheme, Functional plasmonics for biosensing applications. HKD 500,000.
  • 2009, GRF (Co-I), To develop a novel surface plasmon resonance biosensor for real-time DNA amplification and detection, HKD 488,109.
  • 2009, GRF (PI), Suppression of caspase 3 by a novel non-coding RNA CUDR: A miRNA Perspective. HKD 1,080,520.
  • 2009, GRF (Co-I), Femtosecond-laser-induced transfection of living cells with foreign DNA. HKD 462,219.
  • 2008, QEF (Co-I), The development of student-Oriented Teaching and Learning resources in Science and a Science Enrichment Programme for Secondary 3-4 students. HKD 3,500,000.
  • 2008, GRF (Co-I), Integrated wide dynamic range photonic biosensors and label-free DNA detection using surface-plasmon enhanced magneto-optical phase change. HKD 769,790.
  • 2008, GRF (Co-I), A novel regulator of insulin release by HMG CoA reductase inhibitors (statins) in porcine isolated pancreatic islets beta-cells. HKD 1,085,729.
  • 2008, UGC Special Equipment Grant (Co-I), Acquisition of fluorescence lifetime imaging (FLIM) system, HKD 4,098,173.
  • 2008, ITF (Tier 3), Phase-sensitive surface plasmon resonance biosensors for healthcare applications. HK$ 999,350.
  • 2008, GRF, Femtosecond-laser-induced fusion of living cells with liposomes for the delivery of foreign DNA. HKD 462,219.
  • 2008, GRF, Integrated wide dynamic range photonic biosensors and label-free DNA detection using surface-plasmon-enhanced magneto-optical phase change. HKD 769,790.
  • 2007, GRF, Electro-optically tunable surface plasmon resonance biosensor micro-arrays. HKD 557,700.
  • 2006, Funding from The Hong Kong Jockey Club Charities Trust - CE Community, To set up food composition database for nutrition labeling. HKD 17,770,000.
  • 2006, RGC Earmarked Grants, Phase imaging of surface plasmon resonance and sensor surface engineering for multi-analyte biosensor chips. HKD 448,000.
  • 2006, RGC Earmarked Grants, Regulation of therapeutics induced apoptosis in human cancer cells by an apoptotic factor on chromosome 1q. HKD 884,957.
  • 2006, Funding from Shun Hing Institute of Advanced Engineering, Photonic biosensor microarrays diagnostics applications. HKD 724,000.
  • 2006, QEF, A science enrichment programme for secondary 3-4 students. HKD 2,000,000.
  • 2004, QEF, Case-based learning of high school science subjects to support learning to learn. HKD 2,820,000.
  • 2005, RGC Earmarked Grants, Riboregulator modulation of drug resistance in human cancer cells. HKD 939,968.
  • 2003, RGC Earmarked Grants, Bioassay-guided isolation, characterization, and mechanistic study of the bioactive components from Paeonia lactiflora, Sophora flavescens, Oldenlandia diffusa and Scutellaria barata for the anti-proliferative effect on human hepatoma cells in vitro and in vivo. HKD 716,000.
  • 2003, Funding from Greater China Technology Group Limited, Study of immunomodulatory activities of Herbsnsenses TM Cordyceps in healthy subjects: A randomized double-blind placebo-controlled cross-over study. HKD 1,118,000.
  • 2003, RGC Earmarked Grants, Establishment of a SARS coronavirus protein/peptide library and an antibody library as common platforms for biological and medical applications. HKD 800,000.
  • 2002, Shanghai/Hong Kong/Anson Research Foundation,, Mechanistic study of anti-tumour effect of natural and synthetic saponins. HKD 1,325,000.
  • 2001, RGC Earmarked Grants, Functional analysis of a novel gene over-expressed in doxorubicin resistant human cancer cells. HKD 699,600.
  • 1994, RGC Earmarked Grants, Signal transduction in normal macrophages & macrophage cell lines. HKD 1,291,000.
  • 1992, RGC Earmarked Grants, Signal transduction in PU5-1.8 cells & normal macrophages. HKD 372,000. [This project was externally assessed and ranked “EXCELLENT” by the RGC panel.]

Patents:
1) HP Ho, CL Wong, SY Wu, WC Law, Chinlon Lin and SK Kong, Optical sensing devices with SPR sensors based on differential phase interrogation and measuring method using the same, U.S. Patent 7365855 (FULL PATENT, 04/2008).
2) HP Ho, SY Wu, C. Lin, SK Kong, Surface plasmon resonance sensors and method for detecting samples using the same, U.S. Patent 7407817 (FULL PATENT, 08/2008).
3) SY Wu, HP Ho, YK Suen, SK Kong, WW Wong, KC Lo, Method and Apparatus for Phase Sensitive Surface Plasmon Resonance, U.S. 8169617 (FULL PATENT, 03/2009).
4) HP Ho, SY Wu, C. Lin, SK Kong, Surface plasmon resonance sensors and method for detecting samples using the same, U.S. Patent 7892855 (FULL PATENT, 02/2011).
5) Chen QL, Ho HP, Kong SK, Kwan PKL, Kwan YW, Kwok HC, Shum P, Suen YK, Wu SY, Yang AKL, Zhou JQ. Microfluidic platform and method for controlling the same. U.S. 20150027555 A1(FULL PATENT, 01/2015).

Awards

•     VC Exemplary Teaching Award (2013)
•     Faculty Exemplary Teaching Award (2013)

Awards Received by Graduate Students

•   CHUK Young Scholars Thesis Awards 2015 (Dr. Jacky LOO Fong Chuen). 

•   Second runner-up of the "Challenge Cup" National Competition – Hong Kong Regional Final, 2017. (Ms. Iris LAW Lok Gi)